I've started working on a Binding of Isaac "let's play" of sorts. It isn't a blind playthrough - I know quite a bit about the game. The main reason I've decided to start it as a personal challenge, but if it garners even a small audience I'll likely continue it for some time to come.
The current schedule is 1 episode per day, usually put up between 12 and 4PM CST. I may look into recording some other indie games at a later date, but the primary focus is Isaac for now.
You can check out the channel at youtube.com/roocey93.
Feel free to subscribe to the channel if you enjoy the content produced thus far. You can also check out my twitter to see when new videos are uploaded.